Peripheral Vascular Disease
Peripheral vascular disease, or PVD, is a condition in which the
arteries that carry blood to the arms or legs become narrowed or
clogged. This interferes with the normal flow of blood, sometimes
causing pain but often causing no symptoms at all.
Angiograph |
The most common cause of PVD is atherosclerosis (often called hardening
of the arteries). Atherosclerosis is a gradual process in which cholesterol
and scar tissue build up, forming a substance called "plaque" that
clogs the blood vessels. In some cases, PVD may be caused by blood
clots that lodge in the arteries and restrict blood flow.
Those with PVD are at higher risk for heart disease and stroke.
Unfortunately, the disease often goes undiagnosed because many people
do not experience symptoms in the early stages of PVD or they mistakenly
think the symptoms are a normal part of aging.
Under The General Heading of PVD, Specific Conditions Include:
- Aortoiliac Occlusive Disease
- Infrainguinal Occlusive Disease/Claudication
- Renovascular HTN/Insufficiency
- Mesenteric Ischemia
- Carotid/Subclavian Occlusive Disease
- Neurovascular Disease
Facts:
PVD affects 10 million people in the United States and about
1 in 20 people over the age of 50
- Symptomatic constitutes 50% of cases (5 million)
- Only a quarter of PVD sufferers are receiving treatment
- Of these, 2.5 million go undiagnosed
- Of the 2.5 million diagnosed cases, 2.1 million are medically
managed (e.g. exercise)
Risk Factors:
As many as 8 million people in the U.S. may have PVD. The disease
affects everyone, although men are somewhat more likely than women
to have PVD. At highest risk are those:
- over the age of 50
- smokers
- diabetic
- overweight
- people who do not exercise, or who have high blood pressure or
high cholesterol
- a family history of heart or vascular disease
Symptoms:
The most common symptom of PVD is painful cramping in the leg or
hip, particularly when walking. This symptom, also known as "claudication," occurs
when there is not enough blood flowing to the leg muscles during
exercise. The pain typically goes away when the muscles are given
a rest. More than half the people with PVD experience leg pain,
numbness or other symptoms – but many people dismiss these
signs as "a normal part of aging" and don’t seek
medical help. Only about half of those with symptoms have been
diagnosed with PVD and are seeing a doctor for treatment.
Other symptoms may include numbness, tingling or weakness in the
leg. In severe cases, you may experience a burning or aching pain
in your foot or toes while resting, or develop a sore on your leg
or foot that does not heal. People with PVD also may experience a
cooling or color change in the skin of the legs or feet, or loss
of hair on the legs. In extreme cases, untreated PVD can lead to
gangrene, a serious condition that may require amputation of a leg,
foot or toes.
PVD Symptoms
- Leg or hip pain during walking
- The pain stops when you rest
- Numbness, tingling or weakness in the legs
- Burning or aching pain in feet or toes when resting
- Sore on leg or foot that won’t heal
- Cold legs or feet
- Color change in skin of legs or feet
- Loss of hair on legs
Diagnosis:
Angiography is
an X-ray in which a contrast agent, or dye, is injected into a vein
or artery to highlight the blood vessels. This can demonstrate the
location of blockages in the blood vessel that may benefit from interventional
treatment. Angiography also is used to guide thin tubes called catheters
to the site of the problem and administer treatments
Venous & Arterial Doppler Ultrasound creates pictures
using sound waves can determine whether there is blockage in the
arteries. Some physicians recommend ultrasound screening for those
who have been diagnosed with atherosclerosis or other risk factors
for peripheral vascular disease. In the ultrasound image shown here,
normal blood flow is in red. Blue areas show where flow is obstructed
by a blockage in the artery.
Magnetic Resonance (MR) Angiography is
a non-invasive diagnostic technique that creates an image of the
blood vessels. A magnetic resonance (MR) scanner uses harmless but
powerful magnetic fields and radio waves to create detailed images
of the body's tissues.
Computed Tomography (CT) Angiography uses computers and x-rays
to generate detailed pictures of the blood vessels, and can be helpful
for planning of interventional procedures.